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Our group studies the molecular basis of plant innate immunity. We aim at deciphering the signaling events linking perception of pathogen-associated molecular patterns (PAMPs) to the establishment of immunity.

We use the leucine-rich repeats receptor kinases EFR and FLS2, which perceive bacterial EF-Tu and flagellin, respectively, as model pattern recognition receptors (PRRs).

Our work also aims at understanding how plant receptor kinases work at the molecular level and how signaling specificity is achieved between different receptor kinase-mediated signaling pathways involved in immunity and growth.

We are also exploring how outcomes of our research can be used to engineer sustainable broad-spectrum disease resistance in crops.

Latest Publications

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Perraki A, Gronnier J, Gouguet P, Boudsocq M, Deroubaix A-F, Simon V , German-Retana S , Zipfel C , Bayer E, Mongrand S, Germain V (2017)

The plant calcium-dependent protein kinase CPK3 phosphorylates REM1.3 to restrict viral infection. bioRxiv preprint Oct 19, 2017 doi: https://doi.org/10.1101/205765

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Boschi F, Schvartzman C, Murchio S, Ferreira V, Siri MI, Galván GA, Smoker M, Stransfeld L, Zipfel C, Vilaró FL, Dalla-Rizza M (2017)

Enhanced Bacterial Wilt Resistance in Potato Through Expression of Arabidopsis EFR and Introgression of Quantitative Resistance from Solanum commersonii. Front. Plant Sci., 25 September 2017 | https://doi.org/10.3389/fpls.2017.01642

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Imkampe J, Halter T, Huang S, Schulze S, Mazzotta S, Schmidt N, Manstretta R, Postel S, Wierzba M, Yang Y, vanDongen WM, Stahl M, Zipfel C, Goshe MB, Clouse S, de Vries SC, Tax F, Wang X, Kemmerling B (2017)

The Arabidopsis Leucine-rich Repeat Receptor Kinase BIR3 Negatively Regulates BAK1 Receptor Complex Formation and Stabilizes BAK1. Plant Cell. 2017 Aug 25. pii: tpc.00376.2017. doi: 10.1105/tpc.17.00376.

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D'Ambrosio JM, Couto D, Fabro G, Scuffi D, Lamattina L, Munnik T, Andersson MX, Alvarez ME, Zipfel C, Laxalt AM (2017)

Phospholipase C2 Regulates MAMP-Triggered Immunity by Modulating ROS Production in Arabidopsis. Plant Physiol. 2017 Aug 21. pii: pp.00173.2017. doi: 10.1104/pp.17.00173.

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