My group studies the molecular basis of plant innate immunity. We aim at deciphering the signaling events linking perception of pathogen-associated molecular patterns (PAMPs) to the establishment of immunity. We use the leucine-rich repeats receptor kinases EFR and FLS2, which perceive bacterial EF-Tu and flagellin, respectively, as model pattern recognition receptors (PRRs).
Our work also aims at understanding how plant receptor kinases work at the molecular level and how signaling specificity is achieved between different receptor kinase-mediated signaling pathways involved in immunity and growth.
We are also exploring how outcomes of our research can be used to engineer sustainable broad-spectrum disease resistance in crops.
The group is based both at TSL and at the University of Zurich (Switzerland). In addition to our own research, we also collaborate with researchers across TSL and contribute to joint research programmes.
Senior Group LeaderThe Sainsbury Laboratory, Norwich, UK.
ProfessorUniversity of East Anglia, Norwich, UK
ProfessorUniversity of Zurich, Zurich, CH
2013 - 2014
Honorary ProfessorUniversity of East Anglia, Norwich, UK
2011 - 2013
Honorary ReaderUniversity of East Anglia, Norwich, UK
2007 - 2018
Associate Faculty MemberJohn Innes Centre, Norwich, UK
2007 - 2011
Group LeaderThe Sainsbury Laboratory, Norwich, UK
2005 - 2007
EMBO long-term Postdoctoral FellowThe Sainsbury Laboratory, Norwich, UK
2001 - 2005
PhD research projectFriedrich-Miescher Institute for Biomedical Research and the Botanical Institute, University of Basel, Switzerland
2001 - 2001
DEA (MSc) in Plant Cellular and Molecular PhysiologyUniversity of Paris XI, France