Synthetic Biology at The Sainsbury Laboratory was formed in May 2013.
We design and develop molecular tools to engineer genomes and use natural and synthetic biological parts to produce novel functions in plant cells.
Our research is centred around the tools and methods for the precise modification of plant genomes, efficient high-order DNA assembly, and developing molecular tools that allow us to detect and understand the molecular interactions between plants and their pathogens.
Bentham AR, Youles M, Mendel MN, Varden FA, De la Concepcion JC, Banfield MJ (2021)
pOPIN-GG: A resource for modular assembly in protein expression vectors. bioRxiv preprint Aug 10, 2021 doi: https://doi.org/10.1101/2021.08.10.455798Read more
Ngou BPM, Ahn HK, Ding P, Redkar A, Brown H, Ma Y, Youles M, Tomlinson L, Jones JDG (2020)
Estradiol-inducible AvrRps4 expression reveals distinct properties of TIR-NLR-mediated effector-triggered immunity. J Exp Bot. 2020 Feb 12. pii: erz571. doi: 10.1093/jxb/erz571.Read more
Ngou BPM, Ahn HK, Ding P, Redkar A, Brown H, Ma Y, Youles M, Tomlinson L, Jones JDG (2019)
Estradiol-inducible AvrRps4 expression reveals distinct properties of TIR-NLR-mediated effector-triggered immunity. bioRxiv preprint Jul 14, 2019 doi: https://doi.org/10.1101/701359Read more
Patron NJ (2016)
Blueprints for green biotech: development and application of standards for plant synthetic biology. Biochem Soc Trans. 44:702-8. doi: 10.1042/BST20160044.Read more