Plant diseases regularly cause severe crop losses that devastate food production for millions of people.

These losses can have enormous humanitarian and economic costs, and the use of crop protection compounds to combat disease can pose environmental and human health risks. Therefore, durable disease resistance solutions are required to assure food security.

Within the 2Blades group, we perform translational research leveraging the advanced understanding of molecular host-pathogen interactions at TSL to deliver new solutions against relevant plant diseases.

These novel discoveries are subsequently developed into products for subsistence and commercial farmers via the 2Blades Foundation and commercial partners.

Latest Publications

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Markell SG, L Tylka G, J Anderson E, van Esse HP (2020)

Developing Public-Private Partnerships in Plant Pathology Extension: Case Studies and Opportunities in the United States. Annu Rev Phytopathol. 2020 Jun 16. doi: 10.1146/annurev-phyto-030320-041359.

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van Esse HP, Reuber L, van der Does D (2019)

GM approaches to improve disease resistance in crops. New Phytol. 2019 May 28. doi: 10.1111/nph.15967.

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Courville KJ, Frantzeskakis L, Gul S, Haeger N, Kellner R, Heßler N, Day B, Usadel B, Gupta YK, van Esse HP, Brachmann A, Kemen E, Feldbrügge M, Göhre V (2019)

Smut infection of perennial hosts: the genome and the transcriptome of the Brassicaceae smut fungus Thecaphora thlaspeos reveal functionally conserved and novel effectors. New Phytol. 2019 Jan 21. doi: 10.1111/nph.15692.

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Moscou MJ, van Esse HP (2017)

The quest for durable resistance. Science: Vol. 358, Issue 6370, pp. 1541-1542 DOI: 10.1126/science.aar4797

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