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Jonathan Jones Group

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We are interested in how plants resist disease, and in how resistance is overcome by pathogens.  To suppress host defence, pathogens secrete effector proteins into plant cells or into their apoplastic spaces.  How these effectors work, and the identity of their targets in the host, help us understand plant defence mechanisms.

We work on the following problems.

  1. How do plant NB-LRR disease resistance proteins recognize pathogen effectors and then activate defence?
  2. What are the effectors of the Arabidopsis downy mildew and white rust pathogens (Hyaloperonospora arabidopsidis and Albugo sp), and how do they suppress host defences?
  3. Can we find and clone new sources of resistance to potato late blight from wild Solanum species?

Latest Publications

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Saucet SB, Ma Y, Sarris PF, Furzer OJ, Sohn KH, Jones JDG (2015)

Two linked pairs of Arabidopsis TNL resistance genes independently confer recognition of bacterial effector ​AvrRps4. Nature Communications 6, Article number: 6338 doi:10.1038/ncomms7338

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Xu F, Zhu C, Cevik V, Johnson K, Liu Y, Sohn K, Jones JD, Holub EB, Li X (2015)

Autoimmunity conferred by chs3-2D relies on CSA1, its adjacent TNL-encoding neighbour. Scientific Reports 5, Article number: 8792 doi:10.1038/srep08792

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McMullan M, Gardiner A, Bailey K, Kemen E, Ward BJ, Cevik V, Robert-Seilaniantz A, Schultz-Larsen T, Balmuth A, Holub E, van Oosterhout C, Jones JD (2015)

Evidence for suppression of immunity as a driver for genomic introgressions and host range expansion in races of Albugo candida, a generalist parasite. Elife. 2015 Feb 27;4. doi: 10.7554/eLife.04550.

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Steuernagel B, Jupe F, Witek K, Jones JD, Wulff BB (2015)

NLR-parser: Rapid annotation of plant NLR complements. Bioinformatics. 2015 Jan 12. pii: btv005. [Epub ahead of print]

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