Back

Jonathan Jones Group

Connect with this group

We are interested in how plants resist disease, and in how resistance is overcome by pathogens.  To suppress host defence, pathogens secrete effector proteins into plant cells or into their apoplastic spaces.  How these effectors work, and the identity of their targets in the host, help us understand plant defence mechanisms.

We work on the following problems.

  1. How do plant NB-LRR disease resistance proteins recognize pathogen effectors and then activate defence?
  2. What are the effectors of the Arabidopsis downy mildew and white rust pathogens (Hyaloperonospora arabidopsidis and Albugo sp), and how do they suppress host defences?
  3. Can we find and clone new sources of resistance to potato late blight from wild Solanum species?

Latest Publications

View all

Asai et al PLOS Path 2014

Asai S, Rallapalli G, Piquerez SJM, Caillaud MC, Furzer OJ, Ishaque N, Wirthmueller L, Fabro G, Shirasu K, Jones JDG (2014)

Expression Profiling during Arabidopsis/Downy Mildew Interaction Reveals a Highly-Expressed Effector That Attenuates Responses to Salicylic Acid. PLoS Pathog 10(10): e1004443. doi:10.1371/journal.ppat.1004443

Read more

Wirthmueller L, Roth C, Fabro G, Caillaud MC, Rallapalli G, Asai S, Sklenar J, Jones AM, Wiermer M, Jones JD, Banfield MJ. (2014)

Probing formation of cargo/importin-α transport complexes in plant cells using a pathogen effector. Plant Journal (2014) doi: 10.1111/tpj.12691

Read more

Weßling R, Epple P, Altmann S, He Y, Yang L, Henz SR, McDonald N, Wiley K, Bader KC, Gläßer C, Mukhtar MS, Haigis S, Ghamsari L, Stephens AE, Ecker JR, Vidal M, Jones JD, Mayer KF, Ver Loren van Themaat E, Weigel D, Schulze-Lefert P, Dangl JL, Panstruga R, Braun P. (2014)

Convergent Targeting of a Common Host Protein-Network by Pathogen Effectors from Three Kingdoms of Life. Cell Host & Microbe 16: 364 – 375 (2014) DOI: http://dx.doi.org/10.1016/j.chom.2014.08.004

Read more

Kamoun S, Furzer O, Jones JD, Judelson HS, Ali GS, Dalio RJ, Roy SG, Schena L, Zambounis A, Panabières F, Cahill D, Ruocco M, Figueiredo A, Chen XR, Hulvey J, Stam R, Lamour K, Gijzen M, Tyler BM, Grünwald NJ, Mukhtar MS, Tomé DF, Tör M, Van den Ackerveken G, McDowell J, Daayf F, Fry WE, Lindqvist-Kreuze H, Meijer HJ, Petre B, Ristaino J, Yoshida K, Birch PR, Govers F. (2014)

The Top 10 oomycete pathogens in molecular plant pathology. Mol Plant Pathol. 2014 Sep 1. doi: 10.1111/mpp.12190. [Epub ahead of print] PubMed PMID: 25178392.

Read more