Jonathan Jones Group

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We are interested in how plants resist disease, and in how resistance is overcome by pathogens.  To suppress host defence, pathogens secrete effector proteins into plant cells or into their apoplastic spaces.  How these effectors work, and the identity of their targets in the host, help us understand plant defence mechanisms.

We work on the following problems.

1) How do plant NB-LRR disease resistance proteins recognize pathogen effectors and then activate defence?

2) What are the effectors of the Arabidopsis downy mildew and white rust pathogens (Hyaloperonospora arabidopsidis and Albugo sp), and how do they suppress host defences?

3) Can we find and clone new sources of resistance to potato late blight from wild Solanum species?

Please see our Group Homepage for further details.

Latest Publications

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Castel B, Fairhead S, Furzer OJ, Redkar A, Wang S, Cevik V, Holub EB, Jones JDG (2021)

Evolutionary trade-offs at the Arabidopsis WRR4A resistance locus underpin alternate Albugo candida recognition specificities. bioRxiv preprint Mar 29, 2021 doi:

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Furzer OJ, Cevik V, Fairhead S, Bailey K, Redkar A, Schudoma C, MacLean D, Holub EB, Jones JDG (2021)

An improved assembly of the Albugo candida Ac2V genome reveals the expansion of the “CCG” class of effectors. bioRxiv preprint Mar 29, 2021 doi:

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Redkar A, CevikV, Bailey K, Furzer OJ, Fairhead S, Borhan MH, Holub EB, Jones JDG (2021)

The Arabidopsis WRR4A and WRR4B paralogous NLR proteins both confer recognition of multiple Albugo candida effectors. bioRxiv preprint Mar 29, 2021 doi:

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Ngou BPM, Ahn HK, Ding P, Jones JDG (2021)

Mutual potentiation of plant immunity by cell-surface and intracellular receptors. Nature (2021).

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