I lead the training of postgraduates at TSL. I coordinate and help deliver face-to-face and online activities with pre-doctoral interns through to early career researchers. For example, I am the Course Director of a new one-year taught MSc in Global Plant Health. New developments include a massive open online course (MOOC) in Global Challenges in Plant Pathology. I also contribute to The Sainsbury Laboratory’s communication and public engagement activities.
Stephen.Bornemann@tsl.ac.uk
Research ID: K-2938-2012
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Pseudomonas syringae addresses distinct environmental challenges during plant infection through the coordinated deployment of polysaccharides. bioRxiv preprint Jun 18, 2021 doi: https://doi.org/10.1101/2021.06.18.449010
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Trehalose and α-glucan mediate distinct abiotic stress responses in Pseudomonas aeruginosa. PLoS Genet 17(4): e1009524. https://doi.org/10.1371/journal.pgen.1009524
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A temperature-sensitive Mycobacterium smegmatis glgE mutation leads to a loss of GlgE enzyme activity and thermostability and the accumulation of α-maltose-1-phosphate. Biochim Biophys Acta Gen Subj. 2020 Nov 6:129783. doi: 10.1016/j.bbagen.2020.129783.
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Trehalose and α-glucan mediate distinct abiotic stress responses in Pseudomonas aeruginosa. bioRxiv preprint Oct 23, 2020 doi: https://doi.org/10.1101/2020.10.23.351924
Read moreThe molecular basis for a temperature-sensitive Mycobacterium smegmatis glgE mutant. bioRxiv preprint Apr 23, 2020 doi: https://doi.org/10.1101/2020.04.23.057067
Read moreMetabolic network for the biosynthesis of intra- and extracellular α-glucans required for virulence of Mycobacterium tuberculosis. PLoS Pathog 12, e1005768. http://doi.org/10.1371/JOURNAL.PPAT.1005768
Assembly of α-glucan by GlgE and GlgB in mycobacteria and streptomycetes. Biochemistry 55, 3270–3284. http://doi.org/10.1021/ACS.BIOCHEM.6B00209
Calcium ion binding properties of Medicago truncatula calcium/calmodulin-dependent protein kinase. Biochemistry 51, 6895-6907. http://doi.org/10.1021/BI300826M
Structure of a Streptomyces maltosyltransferase GlgE: a homologue of a genetically validated anti-tuberculosis target. J Biol Chem. 286, 38298-38310. http://doi.org/10.1074/JBC.M111.279315
Self-poisoning of Mycobacterium tuberculosis by targeting GlgE in an α-glucan pathway. Nature Chem Biol 6, 376-384. http://doi.org/10.1038/NCHEMBIO.340
Barley (Hordeum vulgare) oxalate oxidase is a manganese-containing enzyme. Biochem J 343, 185-190. http://doi.org/10.1042/0264-6021:3430185
2020 – present Director of Postgraduate Research and Training, The Sainsbury Laboratory, Norwich, UK
2017 – 2020 Postgraduate Research Director, John Innes Centre, Norwich, UK
1996 – 2017 Group Leader, John Innes Centre, Norwich, UK
1992 – 1995 Postdoc, Nitrogen Fixation Laboratory, Sussex University, UK
1989 – 1992 PhD Chemistry, Warwick University, UK
1987 – 1989 Research Scientist, Tate & Lyle Research & Technology, Reading University, UK
1986 – 1987 MSc Biotechnology, University College London, UK
1983 – 1986 BSc Biochemistry, King’s College London, UK