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Daniel Lüdke

Post-doctoral Scientist
Sophien Kamoun Group

I am fascinated by the mechanisms that lead to the induction of immune responses in plants after pathogen recognition. In my current project at TSL, I aim to investigate the molecular components and mechanisms that regulate NLR receptor networks using proteomics and transcriptomics approaches.

Publications

Lüdke D, Roth C, Kamrad SA, Messerschmidt J, Hartken D, Appel J, Hörnich BF, Yan Q, Kusch S, Klenke M, Gunkel A, Wirthmueller L, Wiermer M (2021)

Functional requirement of the Arabidopsis importin-α nuclear transport receptor family in autoimmunity mediated by the NLR protein SNC1. Plant J. 2021 Feb;105(4):994-1009. doi: 10.1111/tpj.15082

Ao K, Tong M, Li L, Lüdke D, Lipka V, Chen S, Wiermer M, Li X (2021)

SCFSNIPER7 controls protein turnover of unfoldase CDC48A to promote plant immunity. New Phytol. 2021 Mar;229(5):2795-2811. doi: 10.1111/nph.17071

Lüdke D, Roth C, Kamrad SA, Messerschmidt J, Hartken D, Appel J, Hörnich BF, Yan Q, Kusch S, Klenke M, Gunkel A, Wirthmueller L, Wiermer M (2020)

Functional requirement of the Arabidopsis importin-α nuclear transport receptor family in autoimmunity mediated by the NLR protein SNC1. bioRxiv preprint May 10, 2020 doi: https://doi.org/10.1101/2020.05.09.084020

Guzha A, McGee R, Hartken D, Scholz P, Lüdke D, Bauer K, Wenig M, Zienkiewicz K, Feussner I, Vlot CA, Wiermer M, Haughn G, Ischebeck T (2019)

The cell-wall-localised BETA-XYLOSIDASE 4 contributes to immunity of Arabidopsis against Botrytis cinerea. bioRxiv preprint Nov 22, 2019 doi: https://doi.org/10.1101/851170

Rekhter D, Lüdke D, Ding Y, Feussner K, Zienkiewicz K, Lipka V, Wiermer M, Zhang Y, Feussner (2019)

Isochorismate-derived biosynthesis of the plant stress hormone salicylic acid. Science. 2019 Aug 2;365(6452):498-502. doi: 10.1126/science.aaw1720

Rekhter D, Lüdke D, Ding Y, Feussner K, Zienkiewicz K, Lipka V, Wiermer M, Zhang Y, Feussner I (2019)

PBS3 is the missing link in plant-specific isochorismate-derived salicylic acid biosynthesis. bioRxiv Apr 19, 2019 doi: https://doi.org/10.1101/600692

Roth C, Lüdke D, Klenke M, Quathamer A, Valerius O, Braus GH, Wiermer M (2017)

The truncated NLR protein TIR-NBS13 is a MOS6/IMPORTIN-α3 interaction partner required for plant immunity. Plant J. 2017 Dec;92(5):808-821. doi: 10.1111/tpj.13717

Tong M, Kotur T, Liang W, Vogelmann K, Kleine T, Leister D, Brieske C, Yang S, Lüdke D, Wiermer M, Zhang Y, Li X, Hoth S (2017)

E3 ligase SAUL1 serves as a positive regulator of PAMP-triggered immunity and its homeostasis is monitored by immune receptor SOC3. New Phytol. 2017 Sep;215(4):1516-1532. doi: 10.1111/nph.14678

Job History

2021 – present Post-doctoral Scientist, The Sainsbury Laboratory, Norwich, UK

2020 – 2021 Post-doctoral Scientist, University of Goettingen, Goettingen, Germany

2017 – 2020 PhD Student, University of Goettingen, Goettingen, Germany

2017 – 2017 Visiting PhD Student, University of British Columbia, Vancouver, Canada

2014 – 2016 MSc Student in Microbiology and Biochemistry, University of Goettingen, Goettingen, Germany

2011 – 2014 BSc Student in Biology, University of Goettingen, Goettingen, Germany