Yoshihiro Inoue

Postdoctoral Scientist
The 2Blades Group

I am interested in understanding how plant pathogens evolve to adapt to its host plants. My previous works focused on the molecular/genetic mechanisms underlying the host specificity between the host plants and hemibiotrophic fungal pathogens.

In the 2Blades group, I am involved in the project to understand the (effector) biology of the biotrophic fungal pathogen, Phakopsora pachyrhizi, which causes Asian Soybean Rust disease on wide range of legume species.
+44 (0) 1603 450404


Isozumi N, Inoue Y, Imamura T, Mori M, Takano Y, Ohki S (2019)

Ca2+-dependent interaction between calmodulin and CoDN3, an effector of Colletotrichum orbiculare. Biochem Biophys Res Commun. 2019 Jun 30;514(3):803-808. doi: 10.1016/j.bbrc.2019.05.007.

Irieda H, Inoue Y, Mori M, Yamada K, Oshikawa Y, Saitoh H, Uemura A, Terauchi R, Kitakura S, Kosaka A, Singkaravanit-Ogawa S, Takano Y (2019)

Conserved fungal effector suppresses PAMP-triggered immunity by targeting plant immune kinases. Proc Natl Acad Sci U S A. 2019 Jan 8;116(2):496-505. doi: 10.1073/pnas.1807297116.

Wang S, Asuke S, Vy TTP, Inoue Y, Chuma I, Win J, Kato K, Tosa Y (2018)

A new resistance gene in combination with Rmg8 confers strong resistance against Triticum isolates of Pyricularia oryzae in a common wheat landrace. Phytopathology. 2018 May 16. doi: 10.1094/PHYTO-12-17-0400-R.

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Anh VL, Inoue Y, Asuke S, Vy TTP, Anh NT, Wang S, Chuma I, Tosa Y (2018)

Rmg8 and Rmg7, wheat genes for resistance to the wheat blast fungus, recognize the same avirulence gene AVR-Rmg8. Mol Plant Pathol. 2018 May;19(5):1252-1256. doi: 10.1111/mpp.12609.

Azmi NSA, Singkaravanit-Ogawa S, Ikeda K, Kitakura S, Inoue Y, Narusaka Y, Shirasu K, Kaido M, Mise K, Takano Y (2018)

Inappropriate Expression of an NLP Effector in Colletotrichum orbiculare Impairs Infection on Cucurbitaceae Cultivars via Plant Recognition of the C-Terminal Region. Mol Plant Microbe Interact. 2018 Jan;31(1):101-111. doi: 10.1094/MPMI-04-17-0085-FI.

Inoue Y, Vy TTP, Yoshida K, Asano H, Mitsuoka C, Asuke S, Anh VL, Cumagun CJR, Chuma I, Terauchi R, Kato K, Mitchell T, Valent B, Farman M, Tosa Y (2017)

Evolution of the wheat blast fungus through functional losses in a host specificity determinant. Science. 2017 Jul 7;357(6346):80-83. doi: 10.1126/science.aam9654.

Fukunaga S, Sogame M, Hata M, Singkaravanit-Ogawa S, Piślewska-Bednarek M, Onozawa-Komori M, Nishiuchi T, Hiruma K, Saitoh H, Terauchi R, Kitakura S, Inoue Y, Bednarek P, Schulze-Lefert P, Takano Y (2017)

Dysfunction of Arabidopsis MACPF domain protein activates programmed cell death via tryptophan metabolism in MAMP-triggered immunity. Plant J. 2017 Jan;89(2):381-393. doi: 10.1111/tpj.13391.

Yoshida K, Saunders DG, Mitsuoka C, Natsume S, Kosugi S, Saitoh H, Inoue Y, Chuma I, Tosa Y, Cano LM, Kamoun S, Terauchi R (2016)

Host specialization of the blast fungus Magnaporthe oryzae is associated with dynamic gain and loss of genes linked to transposable elements. BMC Genomics. 2016 May 18;17(1):370. doi: 10.1186/s12864-016-2690-6.

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Anh VL, Anh NT, Tagle AG, Vy TT, Inoue Y, Takumi S, Chuma I, Tosa Y (2015)

Rmg8, a New Gene for Resistance to Triticum Isolates of Pyricularia oryzae in Hexaploid Wheat. Phytopathology. 2015 Dec;105(12):1568-72. doi: 10.1094/PHYTO-02-15-0034-R.

Pham KT, Inoue Y, Vu BV, Nguyen HH, Nakayashiki T, Ikeda K, Nakayashiki H (2015)

MoSET1 (Histone H3K4 Methyltransferase in Magnaporthe oryzae) Regulates Global Gene Expression during Infection-Related Morphogenesis. PLoS Genet. 2015 Jul 31;11(7):e1005385. doi: 10.1371/journal.pgen.1005385.

Cumagun CJ, Anh VL, Vy TT, Inoue Y, Asano H, Hyon GS, Chuma I, Tosa Y (2014)

Identification of a hidden resistance gene in tetraploid wheat using laboratory strains of Pyricularia oryzae produced by backcrossing. Phytopathology. 2014 Jun;104(6):634-40. doi: 10.1094/PHYTO-04-13-0106-R.

Vy TTP, Hyon G-S, Nga NTT, Inoue Y, Chuma I, Tosa Y (2013)

Genetic analysis of host-pathogen incompatibility between Lolium isolates of Pyricularia oryzae and wheat. J. Gen. Plant Pathol. 80, 59-65 (2014).

Inoue Y, Mori R, Takahashi Y, Kiguchi S, Enomoto T, Chuma I, Tosa Y (2013)

Identification and molecular mapping of a wheat gene for resistance to an unadapted isolate of Colletotrichum cereale. Phytopathology. 2013 Jun;103(6):575-82. doi: 10.1094/PHYTO-09-12-0216-R.

Nga NT, Inoue Y, Chuma I, Hyon GS, Okada K, Vy TT, Kusaba M, Tosa Y (2012)

Identification of a novel locus Rmo2 conditioning resistance in barley to host-specific subgroups of Magnaporthe oryzae. Phytopathology. 2012 Jul;102(7):674-82. doi: 10.1094/PHYTO-09-11-0256.

Hyon G-S, Nga NTT, Chuma I, Inoue Y, Asano H, Murata N, Kusaba M, Tosa Y (2012)

Characterization of interactions between barley and various host-specific subgroups of Magnaporthe oryzae and M. grisea. J. Gen. Plant Pathol. 78, 237-246 (2012).

Job History

2019 – present Postdoctoral Scientist, The Sainsbury Laboratory, Norwich, UK

2015 – 2019 Postdoctoral Researcher, Kyoto University, Kyoto, Japan

2013 – 2015 Postdoctoral Researcher, Kobe University, Kobe, Japan

2010 – 2013 PhD student, Kobe University, Kobe, Japan