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Dr Xiao Lin

Postdoctoral Scientist
Jonathan Jones Group

I am interested in plant-microbe interaction, especially the interaction between the Irish famine pathogen Phytophthora infestans and potato. I believe this knowledge will help to achieve more durable disease resistance in crop plants.

During my PhD, I focused on the MAMPs and apoplastic effectors from Phytophthora species and hunt for the corresponding surface immune receptors from potatoes. I used Effectoromics strategy to identify the Solanaceae plants which carry the potential surface immune receptors, then applied genetics, genomics, NGS and RLP/KSeq methods to map those surface immune receptors.

At TSL, I am aiming to identify the P. infestans effectors that recognized by NLR receptors from Solanum americanum. Once the effectors are identified, the distribution and evolution of these effectors in world-wide P. infestans races will be studied.

Publications

Aguilera-Galvez C, Champouret N, Rietman H, Lin X, Wouters D, Chu Z, Jones JDG, Vossen JH, Visser RGF, Wolters PJ, Vleeshouwers VGAA (2018)

Two different R gene loci co-evolved with Avr2 of Phytophthora infestans and confer distinct resistance specificities in potato. Stud Mycol. 2018 Mar;89:105-115. doi: 10.1016/j.simyco.2018.01.002.

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Domazakis E, Lin X, Aguilera-Galvez C, Wouters D, Bijsterbosch G, Wolters PJ and Vleeshouwers VGAA (2017)

Effectoromics-based identification of cell surface receptors in potato. In: Shan L., He P. (eds) Plant Pattern Recognition Receptors. Methods in Molecular Biology, vol 1578. Humana Press, New York, NY. pp 337-353.

Derevnina L, Dagdas YF, De la Concepcion JC, Bialas A, Kellner R, Petre B, Domazakis E, Du J, Wu CH, Lin X, Aguilera-Galvez C, Cruz-Mireles N, Vleeshouwers VG, Kamoun S (2016)

Nine things to know about elicitins. New Phytol. 2016 Sep 1. doi: 10.1111/nph.14137.

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Lin X, Zhang Y, Kuang H, Chen J (2013)

Frequent loss of lineages and deficient duplications accounted for low copy number of disease resistance genes in Cucurbitaceae. BMC Genomics. 2013 May 17;14:335. doi: 10.1186/1471-2164-14-335.

Job History

2018 – present Postdoctoral Scientist, The Sainsbury Laboratory, Norwich, UK

2013 – 2018 PhD of Plant Breeding, Wageningen University & Research, Wageningen, Netherlands

2010 – 2013 MSc of Genomics, HuaZhong Agricultural University, Wuhan, China

2006 – 2010 BSc of Biological Science, HuaZhong Agricultural University, Wuhan, China