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Dr Thomas DeFalco

Postdoctoral Scientist
Cyril Zipfel Group

I did my undergraduate and MSc degrees in biology at Queen’s University (Kingston, Canada) with Dr. Wayne Snedden, where I worked on the biochemistry of plant calcium signalling, particularly via the conserved calcium sensor calmodulin. I then pursued my PhD with Dr. Keiko Yoshioka at the University of Toronto (Toronto, Canada), where I worked on cyclic nucleotide-gated channels, with a focus on their regulation and roles in calcium signalling and immunity.

I joined the Zipfel group in 2017 to study signal transduction during plant immunity, with a focus on the characterization of BIK1 substrates.

 

Publications

DeFalco TA, Moeder W, Yoshioka K (2016)

Insights into Cyclic Nucleotide-Gated Channel-Mediated Signaling. Trends in Plant Science 21: 903-906.

DeFalco TA, Marshall CB, Munro K, Kang H-G, Moeder W, Ikura M, Snedden WA, Yoshioka K (2016)

Multiple Calmodulin-Binding Sites Positively and Negatively Regulate Arabidopsis CYCLIC NUCLEOTIDE-GATED CHANNEL12. The Plant Cell 28: 1738-1751.

Chin K, DeFalco TA, Moeder W, Yoshioka K (2013)

The Arabidopsis cyclic nucleotide-gated ion channels AtCNGC2 and AtCNGC4 work in the same signaling pathway to regulate pathogen defense and floral transition. Plant Physiology 163: 611-624.

DeFalco TA, Chiasson D, Munro K, Kaiser BN, Snedden WA (2010)

Characterization of GmCaMK1, a member of a soybean calmodulin-binding receptor-like kinase family. FEBS Letters 584: 4717-4724.

DeFalco TA, Bender KW, Snedden WA (2010)

Breaking the code: Ca2+ sensors in plant signalling. Biochemical Journal 425: 27-40.

Job History

2011 – 2016 PhD, University of Toronto, Canada

2007 – 2010 MSc, Queen’s University, Canada