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Sreya Ghosh

Postdoctoral Scientist
The 2Blades Group

I am interested in using computational approaches to rapidly mine for genes that confer resistance to the devasting Asian Soybean Rust (ASR) pathogen. I work as part of a larger team that aims to introduce robust genetic resistance to ASR in cultivated soybean. During my PhD, I worked on the application and development of tools that allow for rapid mining and characterisation of genes that confer resistance to the devastating wheat rust pathogen. These approaches included both wet lab and glasshouse work in addition to bioinformatics.

Publications

Md. Hatta MA, Ghosh S, Athiyannan N, Richardson T, Steuernagel B, Yu G, Rouse MN, Ayliffe M, Lagudah ES, Radhakrishnan GV, Periyannan SK, Wulff BBH(2020)

Extensive genetic variation at the Sr22 wheat stem rust resistance gene locus in the grasses revealed through evolutionary genomics and functional analyses. Molecular Plant-Microbe Interactions, 33(11), pp.1286-1298.

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Ghosh S, Watson A, Gonzalez-Navarro OE, Ramirez-Gonzalez RH, Yanes L, Mendoza-Suárez M, Simmonds J, Wells R, Rayner T, Green P, Hafeez A, Hayta S, Melton RE, Steed A, Sarkar A, Carter J, Perkins L, Lord J, Tester M, Osbourn A, Moscou MJ, Nicholson P, Harwood W, Martin C, Domoney C, Uauy C, Hazard B, Wulff BBH, Hickey LT (2018)

Speed breeding in growth chambers and glasshouses for crop breeding and model plant research. Nat Protoc. 2018 Nov 16. doi: 10.1038/s41596-018-0072-z.

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Watson A, Ghosh S, Williams MJ, Cuddy WS, Simmonds J, Rey MD, Asyraf Md Hatta M, Hinchliffe A, Steed A, Reynolds D, Adamski NM, Breakspear A, Korolev A, Rayner T, Dixon LE, Riaz A, Martin W, Ryan M, Edwards D, Batley J, Raman H, Carter J, Rogers C, Domoney C, Moore G, Harwood W, Nicholson P, Dieters MJ, DeLacy IH, Zhou J, Uauy C, Boden SA, Park RF, Wulff BBH, Hickey LT (2018)

Speed breeding is a powerful tool to accelerate crop research and breeding. Nature Plants 4, 23–29

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Sánchez-Martín J, Steuernagel B, Ghosh S, Herren G, Hurni S, Adamski N, Vrána J, Kubaláková M, Krattinger SG, Wicker T, Doležel J, Keller B, Wulff BB (2016)

Rapid gene isolation in barley and wheat by mutant chromosome sequencing. Genome Biology 17, 221.

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Job History

2021 – present Postdoctoral Scientist, The Sainsbury Laboratory, Norwich, UK

2020 – 2021 Postdoctoral Scientist, John Innes Centre, Norwich, UK

2016 – 2020 Postgraduate Researcher, John Innes Centre, Norwich, UK