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Mr Sebastian Pfeilmeier

PhD Student
Cyril Zipfel Group

I obtained a MSc degree in Molecular Biotechnology at the Technical University of Munich in Germany. My studies focused mainly on protein biochemistry, microbiology and plant biology. During my master’s thesis in the laboratory of Prof. Hückelhoven, I investigated cell death-regulating proteins in interaction of Arabidopsis thaliana with the adapted powdery mildew fungus Erysiphe cruciferarum.

Parallel to my biological studies, I pursued a postgraduate course in Philosophy of Science and Technology. Nevertheless, I was eager to be back at the bench and joined the Zipfel laboratory in October 2013 as a PhD student co-supervised by Jacob Malone (JIC/UEA) and Rob Field (JIC) funded by a Norwich Research Park Studentship. In my project, I will investigate mechanisms by which commensal and pathogenic bacteria evade plant immunity.

Publications

Pfeilmeier S, Caly DL, Malone JG (2016)

Bacterial pathogenesis of plants: Future challenges from a microbial perspective. Mol Plant Pathol. 2016 May 12. doi: 10.1111/mpp.12427

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Little RH, Grenga L, Saalbach G, Howat AM, Pfeilmeier S, Trampari E, Malone JG (2015)

Adaptive Remodeling of the Bacterial Proteome by Specific Ribosomal Modification Regulates Pseudomonas Infection and Niche Colonisation. PLoS Genet. 12(2):e1005837. doi: 10.1371/journal.pgen.1005837.

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Pfeilmeier S, Saur IM, Rathjen JP, Zipfel C, Malone JG (2015)

High levels of cyclic-di-GMP in plant-associated Pseudomonas correlate with evasion of plant immunity. Mol Plant Pathol. 2015 Jul 23. doi: 10.1111/mpp.12297.

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Weis, C., Hildebrandt, U., Hoffmann, T., Hemetsberger, C., Pfeilmeier, S., König, C., Schwab, W., Eichmann, R. and Hückelhoven, R. (2014)

CYP83A1 is required for metabolic compatibility of Arabidopsis with the adapted powdery mildew fungus Erysiphe cruciferarum. New Phytologist, 202: 1310–1319

Weis, C., Pfeilmeier, S., Glawischnig, E., Isono, E., Pachl, F., Hahne, H., Kuster, B., Eichmann, R. and Hückelhoven, R. (2013)

Co-immunoprecipitation-based identification of putative BAX INHIBITOR-1-interacting proteins involved in cell death regulation and plant–powdery mildew interactions. Molecular Plant Pathology, 14: 791–802

Job History

2013 – present PhD Student, The Sainsbury Laboratory, Norwich, UK.

2012 – 2013 MSc Philosophy of Science and Technology, Technical University of Munich, Germany.

2010 – 2012 MSc Molecular Biotechnology, Technical University of Munich, Germany.