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Michelle Hulin

Postdoctoral Scientist
Wenbo Ma Group

I am interested in the evolution and population genetics of plant pathogenic bacteria. Specifically, I am interested in understanding how bacteria adapt to cause disease and characterising the mechanisms they use to manipulate plant physiology to overcome host defences. My PhD and subsequent postdoc (at NIAB-EMR/University of Reading) focused on using comparative genomics to investigate the genetic basis of host specificity of Pseudomonas syringae on Prunus species. At TSL, I will explore the role of Nudix-domain effectors in bacteria-plant interactions.

Publications

Yuan X, Hulin MT, Sundin GW (2020)

Effectors, chaperones, and harpins of the Type III secretion system in the fire blight pathogen Erwinia amylovora: a review. Journal of Plant Pathology. Accepted article

Neale HC, Hulin MT, Harrison RJ, Jackson RW, Mansfield JW, Arnold DL (2020)

An improved conjugation method for Pseudomonas syringae. J Microbiol Methods. 2020 Oct;177:106025. doi: 10.1016/j.mimet.2020.106025.

Hulin MT, Jackson RW, Harrison RJ, Mansfield JW (2020)

Cherry picking by pseudomonads: After a century of research on canker, genomics provides insights into the evolution of pathogenicity towards stone fruits. Plant Pathol. 2020 Aug;69(6):962-978. doi: 10.1111/ppa.13189.

Taylor A, Armitage AD, Handy C, Jackson AC, Hulin MT, Harrison RJ, Clarkson JP (2019)

Basal Rot of Narcissus: Understanding Pathogenicity in Fusarium oxysporum f. sp. narcissi. Front Microbiol. 2019 Dec 19;10:2905. doi: 10.3389/fmicb.2019.02905.

Armitage AD, Taylor A, Hulin MT, Jackson AC, Harrison RJ, Clarkson JP (2020)

Draft Genome Sequence of an Onion Basal Rot Isolate of Fusarium proliferatum. Microbiol Resour Announc. 2019 Jan 3;8(1):e01385-18. doi: 10.1128/MRA.01385-18.

Hulin MT, Armitage AD, Vicente JG, Holub EB, Baxter L, Bates HJ, Mansfield JW, Jackson RW, Harrison RJ (2018)

Comparative genomics of Pseudomonas syringae reveals convergent gene gain and loss associated with specialization onto cherry (Prunus avium). New Phytol. 2018 Jul;219(2):672-696. doi: 10.1111/nph.15182.

Hulin MT, Mansfield JW, Brain P, Xu X, Jackson RW, Harrison RJ (2018)

Characterization of the pathogenicity of strains of Pseudomonas syringae towards cherry and plum. Plant Pathol. 2018 Jun;67(5):1177-1193. doi: 10.1111/ppa.12834.

Li B, Hulin MT, Brain P, Mansfield JW, Jackson RW, Harrison RJ (2015)

Rapid, automated detection of stem canker symptoms in woody perennials using artificial neural network analysis. Plant Methods. 2015 Dec 24;11:57. doi: 10.1186/s13007-015-0100-8.

Sharpe B, Hulin M, Thorne-Wallis J, Wheals A (2014)

Rapid identification of the genus Dekkera/Brettanomyces, the Dekkera subgroup and all individual species. Int J Food Microbiol. 2014 Sep 18;187:7-14. doi: 10.1016/j.ijfoodmicro.2014.06.028.

Sharpe B, Hulin M, Thorne-Wallis J, Stratford M, Wheals AE (2013).

Synteny analysis provides a route to design genus-specific PCR primers for rapid identification of all Saccharomyces species. FEMS Yeast Research, 14(3), p. 517-25.

Hulin M. Wheals, AE (2014)

Rapid identification of Zygosaccharomyces with genus-specific primers. International Journal of Food Microbiology, 173(1), p.9-13.

Job History

2020 – present Postdoctoral Scientist, The Sainsbury Laboratory, Norwich, UK

2017 – 2020 Postdoctoral Scientist, NIAB EMR, UK

2013 – 2017 PhD in Biological Sciences, NIAB EMR/University of Reading, UK

2010 – 2013 BSc in Biological Sciences, University of Bath, UK