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Dr Michaela Kopischke

Postdoctoral Scientist
Silke Robatzek Group

Plants have evolved a plethora of defence strategies against pathogen infection. Membrane compartments reposition and accumulate at the plant cell-pathogen interface and the secretory-endosomal trafficking network is engaged by the plant’s immune system to actively defend against potential pathogens. Reciprocally, invasive pathogens have evolved means to utilize these trafficking pathways to promote microbial proliferation. My research focusses on the elucidation of these trafficking processes and the identification of key regulatory components that are involved in mediating immunity.

In Silke Robatzek’s group, my aim is to understand the molecular mechanisms by which membrane trafficking controls stomatal immunity, an important layer of the plant’s immune system. A main approach in my research is live cell imaging.

Dr Michaela Kopischke

michaela.kopischke@tsl.ac.uk
+44 (0) 1603 450402

Publications

Woolfenden HC, Bourdais G, Kopischke M, Miedes E, Molina A, Robatzek S, Morris RJ (2017)

A computational approach for inferring the cell wall properties that govern guard cell dynamics. Plant Journal 92, 5-18.

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Woolfenden HC, Bourdais G, Kopischke M, Miedes E, Molina A, Robatzek S, Morris RJ (2017)

A computational approach for inferring the cell wall properties that govern guard cell dynamics. Plant J. 2017 Jul 25. doi: 10.1111/tpj.13640.

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Petre B, Kopischke M, Evrard A, Robatzek S, Kamoun S (2016)

Cell re-entry assays do not support models of pathogen-independent translocation of AvrM and AVR3a effectors into plant cells. bioRxiv preprint January 29, 2016 doi: http://dx.doi.org/10.1101/038232

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Fuchs R, Kopischke M, Klapprodt C, Hause G, Meyer AJ, Schwarzländer M, Fricker MD, Lipka V (2015)

Immobilized subpopulations of leaf epidermal mitochondria mediate PEN2-dependent pathogen entry control in Arabidopsis. The Plant Cell December 31, 2015 TPC2015-00887-RA

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Petutschnig EK, Stolze M, Lipka U, Kopischke M, Horlacher J, Valerius O, Rozhon W, Gust AA, Kemmerling B, Poppenberger B, Braus GH, Nürnberger T, Lipka V. (2014)

A novel Arabidopsis CHITIN ELICITOR RECEPTOR KINASE 1 (CERK1) mutant with enhanced pathogen-induced cell death and altered receptor processing. New Phytol. 2014 Jul 10. doi: 10.1111/nph.12920. [Epub ahead of print] PubMed PMID: 25041086.

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McLachlan D, Kopischke M and Robatzek S (2014)

Gate control: guard cell regulation by pathogen stress. New Phytol. Volume 203, Issue 4, pages 1049–1063.

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Petutschnig EK, Stolze M, Lipka U, Kopischke M, Horlacher J, Valerius O, Rozhon W, Gust AA, Kemmerling B, Poppenberger B, Braus GH, Nürnberger T, Lipka V. (2014)

A novel Arabidopsis CERK1 mutant with enhanced pathogen-induced cell death and altered receptor processing. Accepted in New Phytologist

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Kopischke M, Westphal L, Schneeberger K, Clark R, Ossowski S, Wewer V, Fuchs R, Landtag J, Hause G, Dörmann P, Lipka V, Weigel D, Schulze-Lefert P, Scheel D, Rosahl S. (2013)

Impaired sterol ester synthesis alters the response of Arabidopsis thaliana to Phytophthora infestans. Plant Journal 73 (3):456-68

Job History

2013 – present Postdoctoral Scientist, The Sainsbury Laboratory

2012- 2013 Postdoctoral Scientist, Georg-August-University Goettingen, Schwann-Schleiden Centre, Germany

2007 – 2012 PhD Biology, Leibniz Institute of Plant Biochemistry (IPB), Halle (Saale), Germany

2001 – 2007 Diploma in Biology, Martin Luther University, Halle-Wittenberg, Germany