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Mr Matthew Smoker

Team Leader
Tissue Culture & Transformation

I manage the plant tissue culture and media team. My main focus is the production of genetically modified plants (17 different species) and also some plant pathogens, namely Phytophthora spp. The GMOs that we produce are a fundamental and essential resource for researchers here in The Sainsbury Laboratory. We also maintain a modest germplasm collection of different Solanum spp. and cultivars and are responsible for the maintenance of plant cell suspension cultures.

As both departmental Biological Safety Officer (BSO) and Chairman of the JIC Biological Safety Committee, my other duties include the management of DEFRA/FERA licences for plant health controlled material and the maintenance and review of Genetic Modification Risk Assessments (GMRAs) for work with GMOs. I apply for FERA–issued phytosanitary certificates for the exports of certain plant material(s) and am also authorised by FERA to issue Plant Passports for the movement of Solanaceous plant material within the EU.

Mr Matthew Smoker

matthew.smoker@tsl.ac.uk
+44 (0) 1603 450401

Publications

Boschi F, Schvartzman C, Murchio S, Ferreira V, Siri MI, Galván GA, Smoker M, Stransfeld L, Zipfel C, Vilaró FL, Dalla-Rizza M (2017)

Enhanced Bacterial Wilt Resistance in Potato Through Expression of Arabidopsis EFR and Introgression of Quantitative Resistance from Solanum commersonii. Front. Plant Sci., 25 September 2017 | https://doi.org/10.3389/fpls.2017.01642

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Pfeilmeier S, George J, Morel A, Roy S, Smoker M, Stransfeld L, Downie A, Peeters N, Malone J, Zipfel C (2017)

Heterologous expression of the immune receptor EFR in Medicago truncatula reduces pathogenic infection, but not rhizobial symbiosis. bioRxiv preprint Aug 2, 2017 doi: https://doi.org/10.1101/171868

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Hegenauer V, Fürst U, Kaiser B, Smoker M, Zipfel C, Felix G, Stahl M, Albert M (2016)

Detection of the plant parasite Cuscuta reflexa by a tomato cell surface receptor. Science Vol. 353, Issue 6298, pp. 478-481 doi: 10.1126/science.aaf3919

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Ilyas M, Hörger AC, Bozkurt TO, van den Burg HA, Kaschani F, Kaiser M, Belhaj K, Smoker M, Joosten MH, Kamoun S, van der Hoorn RA (2015)

Functional Divergence of Two Secreted Immune Proteases of Tomato. Current Biology 25: 2300–2306.

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Jones JD, Witek K, Verweij W, Jupe F, Cooke D, Dorling S, Tomlinson L, Smoker M, Perkins S, Foster S (2014)

Elevating crop disease resistance with cloned genes. Philosophical Transactions of the Royal Society B 369 20130087

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Schornack, S., van Damme, M., Bozkurt, T.O., Cano, L.M., Smoker, M., Thines, M., Gaulin, E., Kamoun S., and Huitema, E. 2010.

Ancient class of translocated oomycete effectors targets the host nucleus. Proceedings of the National Academy of Sciences USA, 107:17421-17426.

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Lacombe S, Rougon-Cardoso A, Sherwood E, Peeters N, Dahlbeck D, van Esse HP, Smoker M, Rallapalli G, Thomma BPHJ, Staskawicz B, Jones JDG and Zipfel C (2010)

Inter-family transfer of a plant pattern recognition receptor confers broad-spectrum bacterial resistance. Nature Biotechnology, 4 :365-369.

Rivas S, Rougon-Cardoso A, Smoker M, Schauser L, Yoshioka H, Jones JDG. (2004)

CITRX thioredoxin interacts with the tomato Cf-9 resistance protein and negatively regulates defence. EMBO Journal, 23(10): 2156-2165

Gidoni D., Fuss E., Burbidge A., Speckmann G. J., James S., Nijkamp D., Mett A., Feiler J., Smoker M., de Vroomen M. J., Leader D., Liharska T., Coppoolse E., Levin I., de Both M., Schuch W., Jones J. D. G., Taylor I. B. (2003)

Multi-functional T-DNA/Ds tomato lines designed for gene cloning and molecular and physical dissection of the tomato genome. Plant Molecular Biology 51 83-98

Kruger J., Thomas C. M., Golstein C., Dixon M. S., Smoker M., Tang S., Mulder L., Jones J. D. G.(2002)

A tomato cysteine protease required for cf-2- dependent disease resistance and supression of autonecrosis. Science 296 744-747

Wulff B. B. H., Thomas C. M., Smoker M., Grant M., Jones J. D. G.(2001)

Domain swapping and gene shuffling identify sequences required for induction of an Avr-dependent hypersensitive response by the tomato Cf-4 and Cf-9 proteins. Plant Cell 13 255-272

Job History

2003 – present Tissue Culture & Transformation Service Manager, The Sainsbury Laboratory, Norwich, UK.

1997 – 2003 Research Assistant, The Sainsbury Laboratory, Norwich, UK.

1991 – 1997 Scientific Officer, IACR Rothamsted, UK.