
Panstruga R, Moscou MJ (2020)
What is the molecular basis of nonhost resistance? Mol Plant Microbe Interact. 2020 Aug 18. doi: 10.1094/MPMI-06-20-0161-CR.
Read moreMy group’s research focuses on understanding the genetic architecture underlying nonhost resistance. We use natural and induced variation within nonhost species to identify the genetic loci specifying resistance.
Our efforts are concentrated on the cereal rusts and their interaction with several grass species, including barley (Hordeum vulgare) and purple false brome (Brachypodium distachyon).
Our long-term goal is to identify and clone the molecular components underlying nonhost resistance and engineer this resistance in wheat.
matthew.moscou@tsl.ac.uk
+44 (0) 1603 450296
What is the molecular basis of nonhost resistance? Mol Plant Microbe Interact. 2020 Aug 18. doi: 10.1094/MPMI-06-20-0161-CR.
Read moreCloning of the rice Xo1 resistance gene and interaction of the Xo1 protein with the defense-suppressing Xanthomonas effector Tal2h. Mol Plant Microbe Interact. 2020 Aug 4. doi: 10.1094/MPMI-05-20-0131-SC.
Read moreCloning of the rice Xo1 resistance gene and interaction of the Xo1 protein with the defense-suppressing Xanthomonas effector Tal2h. bioRxiv preprint May 29, 2020 doi: https://doi.org/10.1101/2020.05.26.116731
Read moreIdentification of a Locus Conferring Dominant Susceptibility to Pyrenophora tritici-repentis in Barley. Front Plant Sci. 2020 Feb 28;11:158. doi: 10.3389/fpls.2020.00158. eCollection 2020.
Read moreStem rust resistance in wheat is suppressed by a subunit of the mediator complex. Nature Communications volume 11, Article number: 1123 (2020)
Read moreGenome assembly and characterization of a complex zfBED-NLR gene-containing disease resistance locus in Carolina Gold Select rice with Nanopore sequencing. PLoS Genet. 2020 Jan 27;16(1):e1008571. doi: 10.1371/journal.pgen.1008571.
Read moreGenome assembly and characterization of a complex zfBED-NLR gene-containing disease resistance locus in Carolina Gold Select rice with Nanopore sequencing. bioRxiv preprint Jun 20, 2019 doi: https://doi.org/10.1101/675678
Read moreSpeed breeding in growth chambers and glasshouses for crop breeding and model plant research. Nat Protoc. 2018 Nov 16. doi: 10.1038/s41596-018-0072-z.
Components of Brachypodium distachyon resistance to nonadapted wheat stripe rust pathogens are simply inherited. PLoS Genet. 2018 Sep 28;14(9):e1007636. doi: 10.1371/journal.pgen.1007636. eCollection 2018 Sep.
The genetic architecture of colonization resistance in Brachypodium distachyon to non-adapted stripe rust (Puccinia striiformis) isolates. PLoS Genet. 2018 Sep 28;14(9):e1007637. doi: 10.1371/journal.pgen.1007637. eCollection 2018 Sep.
Read moreDetection of race-specific resistance against Puccinia coronata f. sp. avenae in Brachypodium species. Phytopathology. 2018 Jun 20. doi: 10.1094/PHYTO-03-18-0084-R.
Read moreDominant integration locus drives continuous diversification of plant immune receptors with exogenous domain fusions. Genome Biol. 2018 Feb 19;19(1):23. doi: 10.1186/s13059-018-1392-6.
Read moreAn ancient integration in a plant NLR is maintained as a trans-species polymorphism. bioRxiv preprint Dec 25, 2017 doi: https://doi.org/10.1101/239541
Read moreThe quest for durable resistance. Science: Vol. 358, Issue 6370, pp. 1541-1542 DOI: 10.1126/science.aar4797
Read moreMalt Modification and Its Effects on the Contributions of Barley Genotype to Beer Flavor. J. Am. Soc. Brew. Chem. 75(4):354-362, 2017.
Read moreEffects of Barley (Hordeum vulgare L.) Variety and Growing Environment on Beer Flavor. J. Am. Soc. Brew. Chem. 75(4):345-353, 2017.
Read moreDominant integration locus drives continuous diversification of plant immune receptors with exogenous domain fusions. bioRxiv preprint Aug 19, 2017 doi: https://doi.org/10.1101/100834
Read moreDiscovery and characterization of two new stem rust resistance genes in Aegilops sharonensis. Theor Appl Genet. 2017 Mar 8. doi: 10.1007/s00122-017-2882-8.
Read moreSelection of transformation-efficient barley genotypes based on TFA (transformation amenability) haplotype and higher resolution mapping of the TFA loci. Plant Cell Rep. 2017 Feb 15. doi: 10.1007/s00299-017-2107-2.
Read moreDefining the genetic architecture of stripe rust resistance in the barley accession HOR 1428. bioRxiv preprint December 13, 2016 doi: http://dx.doi.org/10.1101/09377
Read moreNatural variation in Brachypodium links vernalization and flowering time loci as major flowering determinants. Plant Physiol. 2016 Sep 20. pii: pp.00813.2016.
Read moreColonization of barley by the broad-host hemibiotrophic pathogen Phytophthora palmivora uncovers a leaf development dependent involvement of MLO. Mol Plant Microbe Interact. 2016 Feb 29.
Read moreIsolation and fine mapping of Rps6: an intermediate host resistance gene in barley to wheat stripe rust. Theor Appl Genet. 2016 doi:10.1007/s00122-015-2659-x
Read moreThe development of quick, robust, quantitative phenotypic assays for describing the host–nonhost landscape to stripe rust. Front. Plant Sci., 27 October 2015
Read moreSequencing of 15,622 gene-bearing BACs clarifies the gene-dense regions of the barley genome. Plant J. 2015 Aug 7. doi: 10.1111/tpj.12959.
Read moreMapping the ‘breaker’ element of the gametocidal locus proximal to a block of sub-telomeric heterochromatin on the long arm of chromosome 4Ssh of Aegilops sharonensis. Theoretical and Applied Genetics DOI 10.1007/s00122-015-2489-x
Read moreStrategies for transferring resistance into wheat: from wide crosses to GM cassettes. Front. Plant Sci., 04 December 2014. doi: 10.3389/fpls.2014.00692
Read moreNonhost resistance to rust pathogens – a continuation of continua. Front. Plant Sci. doi: 10.3389/fpls.2014.00664
Read moreThe infection of Brachypodium distachyon with selected grass rust pathogens. Molecular Plant-Microbe Interactions. 26(8): 946-957.
Read moreCharacterisation and Analysis of the Aegilops sharonensis Transcriptome, a Wild Relative of Wheat in the Sitopsis Section
Read moreAn improved consensus linkage map of barley based on flow-sorted chromosomes and SNP markers. The Plant Genome. 4(3): 238-249.
Read moreQuantitative and qualitative stem rust resistance factors in barley are associated with transcriptional suppression of defense regulons. PLoS Genetics 7(7): e1002208.
Quantitative and temporal definition of the Mla transcriptional regulon during barley-powdery mildew interactions. Molecular Plant-Microbe Interactions 24(6): 694-705.
A Simple Cipher Governs DNA Recognition by TAL Effectors. Science 326: 1501.
2014 – present Group Leader, The Sainsbury Laboratory, Norwich, UK.
2013 – 2014 Team Leader, The Sainsbury Laboratory, Norwich, UK.
2010 – 2012 Research Associate, The Sainsbury Laboratory, Norwich, UK.