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Dr Hiroaki Adachi

Postdoctoral Scientist
Sophien Kamoun Group

I am interested in plant-pathogen interaction, and especially in signalling after pathogen sensing to induce plant immune responses. During my PhD, I focused on MAPK cascade-mediated signalling pathway to understand how plants trigger hypersensitive response (HR) including ROS burst and localized cell death.

My current project focuses on understanding molecular mechanism how NLR proteins sense cognate effectors and initiate downstream signaling to induce HR.

Publications

Yoshioka H, Adachi H, Nakano T, Miyagawa N, Ishihama N, Asai S, Yoshioka M (2016)

Hierarchical regulation of NADPH oxidase by protein kinases in plant immunity. Physiol. Mol. Plant Pathol. 95, 20-16.

Adachi H, Ishihama N, Nakano T, Yoshioka M, Yoshioka H (2016)

Nicotiana benthamiana MAPK-WRKY pathway confers resistance to a necrotrophic pathogen Botrytis cinerea. Plant Signal Behav. 2016 Jun 2;11(6):e1183085. doi: 10.1080/15592324.2016.1183085.

Adachi H, Nakano T, Miyagawa N, Ishihama N, Yoshioka M, Katou Y, Yaeno T, Shirasu K, Yoshioka H (2015)

WRKY Transcription Factors Phosphorylated by MAPK Regulate a Plant Immune NADPH Oxidase in Nicotiana benthamiana. Adachi H, Nakano T, Miyagawa N, Ishihama N, Yoshioka M, Katou Y, Yaeno T, Shirasu K, Yoshioka H

Le Roux C, Huet G, Jauneau A, Camborde L, Trémousaygue D, Kraut A, Zhou B, Levaillant M, Adachi H, Yoshioka H, Raffaele S, Berthomé R, Couté Y, Parker JE, Deslandes L (2015)

A receptor pair with an integrated decoy converts pathogen disabling of transcription factors to immunity. Cell. 2015 May 21;161(5):1074-88. doi: 10.1016/j.cell.2015.04.025.

Adachi H, Yoshioka H (2015)

Kinase-mediated orchestration of NADPH oxidase in plant immunity. Brief Funct Genomics. 2015 Jul;14(4):253-9. doi: 10.1093/bfgp/elv004.

Ishihama N, Adachi H, Yoshioka M, Yoshioka H (2014)

In vivo phosphorylation of WRKY transcription factor by MAPK. “Plant MAP Kinases: Methods and Protocols”, In Methods in Molecular Biology, Vol. 1171, (Komis, G. and Samaj, J. eds) Springer/Humana Press, NY, pp. 171-181.

Job History

2017 – present Postdoctoral Scientist, The Sainsbury Laboratoy, UK

2014 – 2017 PhD Student, Magoya University, Japan