Dr Dae Sung Kim

Postdoctoral Scientist
Jonathan Jones Group

The interaction between Hyaloperonospora arabidopsidis (Hpa) and Arabidopsis is a very useful system to understand the molecular mechanisms of plant immunity.

Pathogen effectors subvert host immunity to successfully colonize the plant. Plants have evolved disease resistance (R) proteins. These recognize effectors either directly or indirectly, and activate effector-triggered immunity (ETI). In the first part, I am interested in the recognition of Hpa effector ATR2 by RPP2A and RPP2B.

Also, HaRxL effectors are thought to manipulate diverse aspects of host physiology for the benefit of the pathogen. Approximately one third of the HaRxLs localize exclusively to the plant cell nucleus and several candidates interact with transcription factors. In the second part, based on previous screenings I focused to around 10 nuclear HaRxLs for further characterization. I am aiming to identify the host targets of these HaRxLs and we will test how they affect early and late read-outs of plant immunity.


Wirthmueller L, Asai S, Rallapalli G, Sklenar J, Fabro G, Kim DS, Lintermann R, Jaspers P, Wrzaczek M, Kangasjärvi L, MacLean D, Menke FLH, Banfield MJ, JDG (2017)

An Oomycete Effector Protein Induces Shade Avoidance In Arabidopsis And Attenuates Salicylate Signaling By Binding To Host Proteins Of The RADICAL-INDUCED CELL DEATH1 Family. bioRxiv preprint May 14, 2017 doi:

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Kim DS, Kim NH, Hwang, BK (2015)

The Capsicum annuum class IV chitinase ChitIV interacts with receptor-like cytoplasmic protein kinase PIK1 to accelerate PIK1-triggered cell death and defence responses. Journal of Experimental Botany 66(7): 1987-1999.

Lim CW, Han SW, Hwang IS, Kim DS, Hwang BK, Lee SC (2015)

The pepper lipoxygenase CaLOX1 plays a role in osmotic, drought, and high salinity. Plant and Cell Physiology 56(5): 930-942

Kim DS, Kim NH, Hwang BK (2014)

Glycine-rich RNA-binding protein1 interacts with receptor-like cytoplasmic protein kinase1 and suppresses cell death and defense responses in pepper (Capsicum annuum). New Phytologist 205(2): 786-800.

Kim DS, Choi HW, Hwang BK (2014)

Pepper mildew resistance locus O interacts with pepper calmodulin and suppresses Xanthomonas AvrBsT-triggered cell death and defense responses. Planta 240(4): 827-839.

Kim, N. H., Kim, D. S., Chung, E. H. and Hwang, B. K. (2014)

Pepper suppressor of the G2 allele of skp1 interacts with the receptor-like cytoplasmic kinase1 and type III effector AvrBsT and promotes the hypersensitive cell death response in a phosphorylation-dependent manner. Plant Physiology 165(1): 76-91

Kim, D. S. and Hwang, B. K. (2014)

An important role of the pepper phenylalanine ammonia-lyase gene (PAL1) in salicylic acid-dependent signalling of the defence response to microbial pathogens. Journal of Experimental Botany 65(9): 2295-2306

Kim, D. S., Jeon, Y. C. and Hwang, B. K. (2014)

The pepper patatin-like phospholipase CaPLP1 functions in plant cell death and defense signalling. Plant Molecular Biology 84(3): 329-344.

Hwang, I. S., Choi, D. S., Kim, N. H., Kim, D. S. and Hwang, B. K. (2014)

Pathogenesis-related protein 4b interacts with leucine-rich repeat protein 1 to suppress PR4b-triggered cell death and defense response in pepper. Plant Journal 77(4): 521-533.

Hwang, I. S., Choi, D. S., Kim, N. H., Kim, D. S. and Hwang, B. K. (2014)

The pepper cysteine/histidine-rich DC1 domain protein CaDC1 binds both RNA and DNA and is required for plant cell death and defense response. New Phytologist 201(2): 518-530.

Choi, H. W., Kim, D. S., Kim, N. H., Jung, H. W., Ham, J. H. and Hwang, B. K. (2013)

Xanthomonas filamentous hemagglutinin-like protein Fha1 interacts with pepper hypersensitive-induced reaction protein CaHIR1 and functions as a virulence factor in host plants. Molecular Plant Microbe Interaction 26(12): 1441-1454.

Kim, D. S. and Hwang, B. K. (2012)

The pepper MLO gene, CaMLO2, is involved in the susceptibility cell-death response and bacterial and oomycete proliferation. Plant Journal 72(5): 843-855.

Lee, D. H., Kim, D. S. and Hwang, B. K. (2012)

The pepper RNA-binding protein CaRBP1 functions in hypersensitive cell death and defense signaling in the cytoplasm. Plant Journal 72(2): 235-248.

Kim, D. S. and Hwang, B. K. (2011)

The pepper receptor-like cytoplasmic protein kinase CaPIK1 is involved in plant signaling of defense and cell-death responses. Plant Journal 66(4): 642-655.

Choi, H. W., Choi, Y. J., Kim, D. S., Hwang, I. S., Choi, D. S., Kim, N. H., Lee, D. H., Shin, H. D., Nam, J. S. and Hwang, B. K. (2009)

First Report of powdery mildew caused by Erysiphe cruciferarum on Arabidopsis thaliana in Korea. The Plant Pathology Journal 25(1): 86-90.

Hong, J. K., Choi, H. W., 1, Hwang, I. S., Kim, D. S., Kim, N. H., Choi, D. S., Kim, Y. J. and Hwang, B. K. (2008)

Function of a novel GDSL-type pepper lipase gene, CaGLIP1 , in disease susceptibility and abiotic stress tolerance. Planta 227(3): 539-558.

Lee, S. C., Kim, D. S., Kim, N. H. and Hwang, B. K. (2007)

Functional analysis of the promoter of the pepper pathogen-induced gene, CAPIP2, during bacterial infection and abiotic stresses. Plant Science 172(2): 236-245.