Simon Saucet

Post Graduate Student

Contact details

Email: simon.saucet@sainsbury-laboratory.ac.uk

Research interests

Plants have a two-layered immune system to prevent pathogen infection (Jones and Dangl, 2006). Pattern recognition receptors (PRR) recognize pathogen associated molecular patterns (PAMPs) which initiates PAMP triggered immunity (PTI). Some plant pathogenic bacteria have evolved a type three secretion system (TTSS) to translocate effector proteins into the plant cell and suppress PTI responses. In turn, plants make resistance (R) proteins able to detect these effectors and trigger an effector-triggered  immunity (ETI). The plant pathogen Pseudomonas syringae carries a TTSS that enable the injection of type three secreted effectors (TTSEs) into its plant hosts. I am interested in the recognition of P. syringae effectors by TIR-NB-LRR proteins in Arabidopsis and in the associated downstream signalling events.