Cyril Zipfel
Project Leader
Contact details
Email: cyril.zipfel@sainsbury-laboratory.ac.uk
Research interests
We are using a combination of forward- and reverse-genetics, as well as biochemical and proteomic approaches to answer the main questions underlying our research programme:
- how are pamp perceived?
- what are the signalling events downstream of pamp perception?
- what is the contribution of pamp perception to plant immunity?
Selected Publications
Nekrasov V, Li J, Batoux M, Roux M, Lacombe S, Rougon A, Chu ZH, Bittel P, Kiss-Papp M, Chinchilla D, van Esse HP, Jorda L, Schwessinger B, Nicaise V, Thomma BPHJ, Molina A, Jones JDG and Zipfel C (2009) Control of the pattern recognition receptor EFR by an ER protein complex in plant immunity. EMBO J, in press.
Li J, Chu ZH, Batoux M, Nekrasov V, Roux M, Chinchilla D, Zipfel C* and Jones JDG (2009) Specific ER quality control components required for biogenesis of the plant innate immune receptor EFR. PNAS, in press.*Corresponding author
Zipfel C (2009) Early molecular events in PAMP-triggered immunity. Curr Opin Plant Biol. 12(4), 414-420.
Chinchilla D, Zipfel C, Robatzek S, Kemmerling B, Nurnberger T, Jones JDG, Felix G and Boller T (2007) A flagellin-induced complex of the receptor FLS2 and BAK1 initiates plant defence. Nature, 448: 497-500.
Zipfel C, Kunze G, Chinchilla D, Caniard A, Jones JDG, Boller T and Felix G (2006) Perception of the bacterial PAMP EF-Tu by the receptor EFR restricts Agrobacterium-mediated transformation. Cell, 125: 749-760.††
Zipfel C, Robatzek S, Navarro L, Oakeley E, Jones JDG, Felix G and Boller T (2004). Bacterial disease resistance through flagellin perception in Arabidopsis. Nature, 428: 764-767
