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Matthew Moscou Group

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Group members

Our research focuses on understanding the genetic architecture underlying host and nonhost resistance. We use natural and induced variation within host, intermediate host, and nonhost species to identify the genetic loci specifying resistance. Our efforts are concentrated on the cereal rusts and their interaction with several grass species, including wheat (Triticum aestivum), barley (Hordeum vulgare), oat (Avena sativa), and purple false brome (Brachypodium distachyon). We apply a suite of approaches to rapidly accelerate our research, including genetics, bioinformatics, molecular biology, and next-generation sequencing.

Current projects in the group include:

– Genetic architecture underlying host species specificity of stripe rust

– Multiple pathogen resistance specificity at the Mla locus

– Map-based cloning of adult plant resistance QTLs to barley stripe rust

– Distribution, diversity, and expression of the barley NB-LRRome

– Nonhost resistance in Brachypodium spp. to wheat stripe rust

– Suppression of resistance in polyploid genomes

 

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Latest Publications

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Yu G, Champouret N, Steuernagel B, Olivera PD, Simmons J, Williams C, Johnson R, Moscou MJ, Hernández-Pinzón I, Green P, Sela H, Millet E, Jones JD, Ward ER, Steffenson BJ, Wulff BB (2017)

Discovery and characterization of two new stem rust resistance genes in Aegilops sharonensis. Theor Appl Genet. 2017 Mar 8. doi: 10.1007/s00122-017-2882-8.

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Hisano H, Meints B, Moscou MJ, Cistue L, Echávarri B, Sato K, Hayes PM

Selection of transformation-efficient barley genotypes based on TFA (transformation amenability) haplotype and higher resolution mapping of the TFA loci. Plant Cell Rep. 2017 Feb 15. doi: 10.1007/s00299-017-2107-2.

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Clare S, Kitcher W, Gardiner M, Green P, Hubbard A, Moscou MJ (2016)

Defining the genetic architecture of stripe rust resistance in the barley accession HOR 1428. bioRxiv preprint December 13, 2016 doi: http://dx.doi.org/10.1101/09377

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Bettgenhaeuser J, Corke FM, Opanowicz M, Green P, Hernández-Pinzón I, Doonan JH, Moscou MJ (2016)

Natural variation in Brachypodium links vernalization and flowering time loci as major flowering determinants. Plant Physiol. 2016 Sep 20. pii: pp.00813.2016.

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