Our group studies wheat genomics and plant innate immunity. We are interested in understanding the molecular basis of plant disease resistance in wheat, a grass that is both amenable to basic research and highly important to agriculture.
Main areas of research are:
1) Development of functional genomic tools for wheat
2) Understanding the fundamental molecular pathways of plant immunity in wheat
3) Isolation of new sources of disease resistance from mutagenized populations
4) Accelerating gene cloning and trait transfer via new genomic technologies
This group is formed by partnership of the Earlham Institute (Triticeae Genomics) and The Sainsbury Laboratory.
Clavijo BJ, Venturini L, Schudoma C, Accinelli GG, Kaithakottil G, Wright J, Borrill P, Kettleborough G, Heavens D, Chapman H, Lipscombe J, Barker T, Lu FH, McKenzie N, Raats D, Ramirez-Gonzalez RH, Coince A, Peel N, Percival-Alwyn L, Duncan O, Trösch J, Yu G, Bolser DM, Namaati G, Kerhornou A, Spannagl M, Gundlach H, Haberer G, Davey RP, Fosker C, Palma FD, Phillips A, Millar AH, Kersey PJ, Uauy C, Krasileva KV, Swarbreck D, Bevan MW, Clark MD (2017)
An improved assembly and annotation of the allohexaploid wheat genome identifies complete families of agronomic genes and provides genomic evidence for chromosomal translocations. Genome Res. 2017. doi: 10.1101/gr.217117.116Read more
Bevan MW, Uauy C, Wulff BBH, Zhou J, Krasileva K, Clark MD (2017)
Genomic innovation for crop improvement. Nature 543, 346–354. doi:10.1038/nature22011Read more
Bailey PC, Dagdas G, Baggs E, Haerty W, Krasileva KV (2017)
Immune receptors with exogenous domain fusions form evolutionary hotspots in grass genomes. bioRxiv preprint January 20, 2017 doi: https://doi.org/10.1101/100834Read more
Krasileva KV, Vasquez-Gross HA, Howell T, Bailey P, Paraiso F, Clissold L, Simmonds J, Ramirez-Gonzalez RH, Wang X, Borrill P, Fosker C, Ayling S, Phillips AL, Uauy C, Dubcovsky J (2017)
Uncovering hidden variation in polyploid wheat. Proc Natl Acad Sci U S A. 2017 Jan 17. pii: 201619268. doi: 10.1073/pnas.1619268114.Read more