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Jonathan Jones Group

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We are interested in how plants resist disease, and in how resistance is overcome by pathogens.  To suppress host defence, pathogens secrete effector proteins into plant cells or into their apoplastic spaces.  How these effectors work, and the identity of their targets in the host, help us understand plant defence mechanisms.

We work on the following problems.

1) How do plant NB-LRR disease resistance proteins recognize pathogen effectors and then activate defence?

2) What are the effectors of the Arabidopsis downy mildew and white rust pathogens (Hyaloperonospora arabidopsidis and Albugo sp), and how do they suppress host defences?

3) Can we find and clone new sources of resistance to potato late blight from wild Solanum species?

Please see our Group Homepage for further details.

Latest Publications

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Arora S, Steuernagel B, Gaurav K, Chandramohan S, Long Y, Matny O, Johnson R, Enk J, Periyannan S, Singh N, Md Hatta MA, Athiyannan N, Cheema J, Yu G, Kangara N, Ghosh S, Szabo LJ, Poland J, Bariana H, Jones JDG, Bentley AR, Ayliffe M, Olson E, Xu SS, Steffenson BJ, Lagudah E, Wulff BBH (2019)

Resistance gene cloning from a wild crop relative by sequence capture and association genetics. Nature Biotechnology 37, 139–143.

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Van de Weyer AL, Monteiro F, Furzer OJ, Nishimura MT, Cevik V, Witek K, Jones JDG, Dangl JL, Weigel D, Bemm F (2019)

The Arabidopsis thaliana pan-NLRome. bioRxiv preprint Jan 31, 2019 doi: https://doi.org/10.1101/537001

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Cevik V, Boutrot F, Apel W, Robert-Seilaniantz A, Furzer OJ, Redkar A, Castel B, Kover PX, Prince DC, Holub EB, Jones JDG (2019)

Transgressive segregation reveals mechanisms of Arabidopsis immunity to Brassica-infecting races of white rust (Albugo candida). Proc. Natl. Acad. Sci. U.S.A. January 28, 2019 https://doi.org/10.1073/pnas.1812911116

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Castel B, Tomlinson L, Locci F, Yang Y, Jones JDG (2019)

Optimization of T-DNA architecture for Cas9-mediated mutagenesis in Arabidopsis. PLoS One. 2019 Jan 9;14(1):e0204778. doi: 10.1371/journal.pone.0204778.