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Jonathan Jones Group

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We are interested in how plants resist disease, and in how resistance is overcome by pathogens.  To suppress host defence, pathogens secrete effector proteins into plant cells or into their apoplastic spaces.  How these effectors work, and the identity of their targets in the host, help us understand plant defence mechanisms.

We work on the following problems.

1) How do plant NB-LRR disease resistance proteins recognize pathogen effectors and then activate defence?

2) What are the effectors of the Arabidopsis downy mildew and white rust pathogens (Hyaloperonospora arabidopsidis and Albugo sp), and how do they suppress host defences?

3) Can we find and clone new sources of resistance to potato late blight from wild Solanum species?

Please see our Group Homepage for further details.

Latest Publications

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Castel B, Tomlinson L, Locci F, Yang Y, Jones JDG (2018)

Optimization of T-DNA architecture for Cas9-mediated mutagenesis in Arabidopsis. bioRxiv preprint Sep 17, 2018 doi: https://doi.org/10.1101/419952

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Wirthmueller L, Asai S, Rallapalli G, Sklenar J, Fabro G, Kim DS, Lintermann R, Jaspers P, Wrzaczek M, Kangasjärvi J, MacLean D, Menke FLH, Banfield MJ, Jones JDG (2018)

Arabidopsis downy mildew effector HaRxL106 suppresses plant immunity by binding to RADICAL-INDUCED CELL DEATH1. New Phytol. 2018 Oct;220(1):232-248. doi: 10.1111/nph.15277.

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International Wheat Genome Sequencing Consortium (2018)

Shifting the limits in wheat research and breeding using a fully annotated reference genome. Science. 2018 Aug 17;361(6403). pii: eaar7191. doi: 10.1126/science.aar7191.

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Shrestha RK, Ding P, Jones JDG, MacLean D (2018)

A workflow for simplified analysis of ATAC-cap-seq data in R. GigaScience, 2017, 1–7. DOI: 10.1093/gigascience/giy080

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