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Jonathan Jones Group

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We are interested in how plants resist disease, and in how resistance is overcome by pathogens.  To suppress host defence, pathogens secrete effector proteins into plant cells or into their apoplastic spaces.  How these effectors work, and the identity of their targets in the host, help us understand plant defence mechanisms.

We work on the following problems.

1) How do plant NB-LRR disease resistance proteins recognize pathogen effectors and then activate defence?

2) What are the effectors of the Arabidopsis downy mildew and white rust pathogens (Hyaloperonospora arabidopsidis and Albugo sp), and how do they suppress host defences?

3) Can we find and clone new sources of resistance to potato late blight from wild Solanum species?

 

Latest Publications

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Mukhi N, Brown H, Gorenkin D, Ding P, Bentham AR, Jones JDG, Banfield MJ (2021)

Perception of structurally distinct effectors by the integrated WRKY domain of a plant immune receptor. bioRxiv preprint Jul 28, 2021 doi: https://doi.org/10.1101/2021.07.28.454147

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Castel B, Fairhead S, Furzer OJ, Redkar A, Wang S, Cevik V, Holub EB, Jones JDG (2021)

Evolutionary trade-offs at the Arabidopsis WRR4A resistance locus underpin alternate Albugo candida race recognition specificities. Plant J. 2021 Jun 28. doi: 10.1111/tpj.15396.

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Ngou BPM, Ding P, Jones JDG (2021)

Channeling plant immunity. Cell. 2021 Jun 24;184(13):3358-3360. doi: 10.1016/j.cell.2021.05.035.

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Lin X, Olave-Achury A, Heal R, Witek K, Karki HS, Song T, Wu CH, Adachi H, Kamoun S, Vleeshouwers VGAA, Jones JDG (2021)

Rpi-amr3 confers resistance to multiple Phytophthora species by recognizing a conserved RXLR effector. bioRxiv preprint Jun 10, 2021 doi: https://doi.org/10.1101/2021.06.10.447899

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